Advil Dual Action Coated Caplets with Acetaminophen are the first FDA approved pain relief medication that combines the top two selling pain fighting ingredients for powerful results. Formulated with 250 mg ibuprofen that targets pain at the source and 500 mg acetaminophen that blocks pain signals in each dose, these coated pain relief pills provide relief from a wide variety of aches and pains. This pain medicine provides headache, toothache, menstrual cramp, muscle pain and lower back pain relief while also relieving minor aches and pains associated with arthritis. The combination of ibuprofen and acetaminophen in these Advil caplets allows you to take a lower maximum daily dose of each pain medication and still have powerful, 8 hour relief (1). Advil is a top selling OTC pain reliever, providing safe and effective pain relief when used as directed for more than 35 years. Get ready to head back to college with confidence and stock up ensuring you\'re ready for anything the academic year throws your way. HSA/FSA eligible product. (1) 8 Hours of Relief - Searle S et al. Claim Substantiation. Clinical Study 2020 February.